United States innovation ecosystem

The Innovative EcoSystems registry lists 40,532 innovation ecosystem organizations in the United States, including 10,487 corporate R&D centers, 10,299 research organizations and 6,125 universities and research institutes.

The largest concentrations are in New York, New York (1,450), Washington, DC (1,418) and Chicago, Illinois (732).

The United States scores 68.5 out of 100 on the IEPA (2024 edition), ranking 21 of 117 economies.

See the United States on the IEPA ↗

40,532 organizations

• Spectral MD (United States)
  Corporate R&D · Dallas · spectralmd.com
• Spectral Platforms (United States)
  Corporate R&D · Monrovia · spectralplatforms.com
• Spectral Sciences (United States)
  Corporate R&D · Burlington · spectral.com
• Spectranetix (United States)
  Corporate R&D · Santa Clara · spectranetix.com
• Spectrasonics (United States)
  Corporate R&D · Wayne · spectrasonics.net
• Spectris (United States)
  Corporate R&D · Libertyville · spectris.com
• Spectros Corporation (United States)
  Corporate R&D · Campbell · spectros.com
• Spectrum Associates (United States)
  Corporate R&D · Milford · spectrumct.com
• Spectrum Brands (United States)
  Corporate R&D · Middleton · spectrumbrands.com
• Spectrum Coatings (United States)
  Corporate R&D · Providence · spectrumcoatings.us
• Spectrum Health
  Health research · Dormant · Grand Rapids · spectrumhealth.org
• Spectrum Magnetics (United States)
  Corporate R&D · Wilmington · spectrum-magnetics.com
• Spectrum Neuroscience and Treatment Institute
  Health research · New York · spectrumneuroscience.com
• Spectrum Pharmaceuticals (United States)
  Corporate R&D · Henderson · sppirx.com
• Spectrum Photonics (United States)
  Corporate R&D · Honolulu · spectrum-photonics.com
• Spectrum Research (United States)
  Corporate R&D · Tacoma · specri.com
• Spectrum Scientific (United States)
  Corporate R&D · Irvine · ssioptics.com
• Speech Processing Solutions (United States)
  Corporate R&D · Alpharetta · speech.com
• SpeechVive (United States)
  Corporate R&D · Lafayette · speechvive.com
• SPEED BioSystems (United States)
  Corporate R&D · Gaithersburg · speedbiosystems.com
• Speedway Fire Rescue
  Research organization · Davenport · speedwayfirerescue.org
• Spelman College
  University or research institute · Atlanta · spelman.edu
• Spencer Foundation
  Research organization · Chicago · spencer.org
• Spencer Industries (United States)
  Corporate R&D · Belleville · spencerindinc.com
• Spencer Technologies (United States)
  Corporate R&D · Redmond · spencertechnologies.com
• Spendr
  Startup · Cincinnati · spendr.com
• Spent Fuel and Waste Disposition
  Government or public body · Washington · energy.gov
• Sperient (United States)
  Corporate R&D · Livermore · sperient.com
• Spero Devices (United States)
  Corporate R&D · Acton · sperodevices.com
• Spero Energy (United States)
  Corporate R&D · West Lafayette · speroenergy.com
• Spero Therapeutics (United States)
  Corporate R&D · Cambridge · sperotherapeutics.com
• Spero Ventures
  Investor or fund · spero.vc
• Spertus Institute for Jewish Learning and Leadership
  University or research institute · Chicago · spertus.edu
• Sphere Institute
  Research organization · Burlingame · sphereinstitute.org
• Spheryx (United States)
  Corporate R&D · New York · spheryx.solutions
• SphingoGene (United States)
  Corporate R&D · Mt. Pleasant · sphingogene.com
• SPI Surgical (United States)
  Corporate R&D · Seattle · spisurg.com
• SpiderOak
  Startup · Overland Park · spideroak.com
• Spina Bifida Association
  Research organization · Arlington · spinabifidaassociation.org
• Spina Bifida Resource Network
  Research organization · Flemington · thesbrn.org
• Spinal Cord Injury Association
  Research organization · Urbandale · spinalcordiowa.wordpress.com
• Spinal Diagnostics and Treatment Center
  Health research · Daly City · spinaldiagnostics.com
• Spinal Elements (United States)
  Corporate R&D · Carlsbad · spinalelements.com
• Spinal Muscular Atrophy Foundation
  Research organization · New York · smafoundation.org
• Spinal Simplicity
  Company · Overland Park · spinalsimplicity.com
• Spindustry
  Company · Des Moines · spindustry.com
• Spine Institute of Louisiana
  Health research · Shreveport · louisianaspine.org
• Spine Institute on the Emerald Coast
  Health research · Destin · emeraldcoastspine.com
• Spine Wave (United States)
  Corporate R&D · Shelton · spinewave.com
• Spineology (United States)
  Corporate R&D · Oakdale · spineology.com
• Spines
  Startup · Boynton Beach · spines.com
• SpineThera (United States)
  Corporate R&D · Plymouth · spinethera.com
• Spiral Foundation
  Research organization · Newton · thespiralfoundation.org
• Spire Global
  Company · Vienna · spire.com
• Spiretronic (United States)
  Corporate R&D · Houston · spiretronic.com
• Spirit AeroSystems (United States)
  Corporate R&D · Wichita · spiritaero.com
• Spirit Lake Consulting (United States)
  Corporate R&D · Fort Totten · spiritlakeconsulting.com
• Spirit Mountain Community Fund
  Research organization · Grand Ronde · thecommunityfund.com
• Spiritech Advanced Products (United States)
  Corporate R&D · Tequesta · spiritech.cc
• Spirituality For Kids International
  Research organization · Los Angeles · sfk.org
• Spitfire Spark Change (United States)
  Corporate R&D · Washington · spitfirestrategies.com
• Splice
  Startup · Norfolk · splice-it.com
• Spline
  Startup · Reston · spline.design
• Split Engineering (United States)
  Corporate R&D · Tucson · spliteng.com
• Splitvane Engineers (United States)
  Corporate R&D · Sumas · splitvane.com
• Splunk (United States)
  Corporate R&D · San Francisco · splunk.com
• Spokane Falls Community College
  University or research institute · Spokane · spokanefalls.edu
• Spokane Public Library
  Organization · Spokane · spokanelibrary.org
• Spondylitis Association of America
  Research organization · Van Nuys · spondylitis.org
• Sponsors for Educational Opportunity
  Research organization · New York · seo-usa.org
• Spontaneous Celebrations
  Science or technology park · spontaneouscelebrations.org
• Spoon River College
  University or research institute · Canton · src.edu
• Sporian Microsystems (United States)
  Corporate R&D · Lafayette · sporian.com
• Sport Foundation
  Research organization · Riverside · sportfoundation.org
• Sportable
  Research organization · Richmond · sportable.org
• Sports Concussion Institute
  Health research · Culver City · concussiontreatment.com
• SportsClub
  Research organization · Greenville · sportsclubsc.com
• Spot Observatory
  University or research institute · Nashville · spotastro.com
• Spot On Sciences (United States)
  Corporate R&D · Austin · spotonsciences.com
• SpotHero
  Company · Chicago · spothero.com
• Spotsylvania County
  Government or public body · Spotsylvania · spotsylvania.va.us
• SPR Therapeutics
  Company · Cleveland · sprtherapeutics.com
• Spragens and Associates (United States)
  Corporate R&D · Durham · lspragens.com
• Spraying Systems Co. (United States)
  Corporate R&D · Glendale Heights · spray.com
• Sprim Advanced Life Sciences
  University or research institute · San Francisco · sprim-als.com
• Spring Arbor University
  University or research institute · Spring Arbor · arbor.edu
• Spring Bank Pharmaceuticals (United States)
  Corporate R&D · Hopkinton · springbankpharm.com
• Spring Hill College
  University or research institute · Mobile · shc.edu
• Spring Lake District Library
  Organization · Spring Lake · sllib.org
• Spring Valley Hospital
  Health research · Spring Valley · springvalleyhospital.com
• SpringActive (United States)
  Corporate R&D · Tempe · springactive.com
• Springboard Foundation
  Research organization · Chicago · springboardfoundation.org
• Springbok Analytics
  Startup · Charlottesville · springbokanalytics.com
• Springboro High School
  University or research institute · Springboro · springboro.org
• Springdale Public Library
  Organization · Springdale · springdalelibrary.org
• Springer Nature (United States)
  Corporate R&D · New York · springernature.com
• Springer Publishing Company (United States)
  Corporate R&D · New York · springerpub.com
• Springfield Clinic
  Health research · Springfield · springfieldclinic.com
• Springfield College
  University or research institute · Springfield · springfield.edu
• Springfield Foundation
  Research organization · Springfield · springfieldfoundation.org
• Springfield Greene County Library District
  Organization · Springfield · thelibrary.org
• Springfield Museums
  Organization · Springfield · springfieldmuseums.org
• Springfield Neurology Clinical Trials
  University or research institute · Springfield · springfieldneurotrials.com
• Springfield Regional Medical Center
  Health research · Springfield · mercy.com
• Springfield Sangamon Growth Alliance
  Government or public body · Springfield · thriveinspi.org
• Springfield Technical Community College
  University or research institute · Springfield · stcc.edu
• Springhouse
  Research organization · Boston · springhouseboston.org
• Springmatter (United States)
  Corporate R&D · Ann Arbor · springmatter.com
• Springstar (United States)
  Corporate R&D · Seattle · springstar.net
• SpringTime Ventures
  Investor or fund · Denver · springtimeventures.com
• Sprint (United States)
  Corporate R&D · Overland Park · sprint.com
• Sprint PNS System (United States)
  Corporate R&D · Cleveland · sprtherapeutics.com
• Sprout Pharmaceuticals, Inc. (United States)
  Corporate R&D · Raleigh · sproutpharmaceuticals.com
• Sprout Social
  Company · Chicago · sproutsocial.com
• SPX Corporation (United States)
  Corporate R&D · Charlotte · spx.com
• SPX Transformer Solutions (United States)
  Corporate R&D · Waukesha · spxtransformersolutions.com
• Spyryx Biosciences (United States)
  Corporate R&D · Durham · spyryxbio.com
• Spytek Aerospace (United States)
  Corporate R&D · Bensenville · spytekaerospace.com
• SPZ Legal
  Company · Denver · spzlegal.com
• Square One (United States)
  Corporate R&D · Jackson · sqr-1.com

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Categories

• Corporate R&D centers in the United States 10,487
• Research organizations in the United States 10,299
• Universities and research institutes in the United States 6,125
• Health research organizations in the United States 4,117
• Government and public bodies in the United States 2,323
• Other organizations in the United States 1,506
• Startups in the United States 1,456
• Companies in the United States 898
• Programs in the United States 707
• Investors and funds in the United States 656
• Networks and associations in the United States 640
• Science and technology parks in the United States 539
• Fab labs and makerspaces in the United States 352
• Innovation hubs in the United States 133
• Accelerators in the United States 116
• Incubators in the United States 110
• Colleges and training providers in the United States 66

Cities

• New York, New York 1,450
• Washington, DC 1,418
• Chicago, Illinois 732
• San Diego, California 485
• Boston, Massachusetts 470
• San Francisco, California 467
• Denver, Colorado 441
• Los Angeles, California 398
• Seattle, Washington 386
• Columbus, Ohio 324
• Boulder, Colorado 323
• Atlanta, Georgia 304
• Houston, Texas 302
• Philadelphia, Pennsylvania 299
• Cambridge, Massachusetts 295
• Cleveland, Ohio 287
• Arlington, Virginia 275
• Cincinnati, Ohio 274
• Austin, Texas 272
• Des Moines, Iowa 237
• Richmond, Virginia 236
• Baltimore, Maryland 225
• Pittsburgh, Pennsylvania 219
• Oklahoma City, Oklahoma 218
• Durham, North Carolina 201
• Portland, Oregon 190
• Dallas, Texas 174
• Madison, Wisconsin 172
• Minneapolis, Minnesota 170
• Bethesda, Maryland 168
• St Louis, Missouri 168
• Oakland, California 167
• Tulsa, Oklahoma 166
• Alexandria, Virginia 162
• Indianapolis, Indiana 162
• Rockville, Maryland 161
• Berkeley, California 159
• Ann Arbor, Michigan 154
• Salt Lake City, Utah 154
• Charlottesville, Virginia 152
• Tucson, Arizona 148
• Wichita, Kansas 148
• San Antonio, Texas 141
• Boca Raton, Florida 140
• Albuquerque, New Mexico 137
• San Jose, California 135
• Miami, Florida 134
• Raleigh, North Carolina 133
• West Palm Beach, Florida 131
• Phoenix, Arizona 128
• Ames, Iowa 125
• Dayton, Ohio 125
• Saint Paul, Minnesota 124
• Sacramento, California 123
• Silver Spring, Maryland 121
• Honolulu, Hawaii 119
• Milwaukee, Wisconsin 112
• Colorado Springs, Colorado 111
• Palo Alto, California 108
• Nashville, Tennessee 107
• Brooklyn, New York 106
• Iowa City, Iowa 100
• Irvine, California 97
• Orlando, Florida 88
• Albany, New York 86
• Champaign, Illinois 86
• Fort Collins, Colorado 86
• Reston, Virginia 86
• Waltham, Massachusetts 86
• Anchorage, Alaska 85
• Greeley, Colorado 85
• Lawrence, Kansas 85
• Louisville, Kentucky 85
• Norfolk, Virginia 85
• Tampa, Florida 85
• Charlotte, North Carolina 83
• Norman, Oklahoma 83
• Kansas City, Missouri 82
• Mountain View, California 81
• New Orleans, Louisiana 81
• Fairfax, Virginia 80
• Huntsville, Alabama 79
• Cedar Rapids, Iowa 78
• Overland Park, Kansas 78
• Santa Fe, New Mexico 77
• Topeka, Kansas 77
• Sunnyvale, California 76
• La Jolla, California 75
• Memphis, Tennessee 74
• McLean, Virginia 73
• Omaha, Nebraska 73
• Pasadena, California 73
• Santa Barbara, California 73
• Santa Clara, California 73
• Akron, Ohio 72
• Baton Rouge, Louisiana 72
• Birmingham, Alabama 72
• Rochester, New York 72
• Little Rock, Arkansas 70
• Hartford, Connecticut 69
• Providence, Rhode Island 69
• Lexington, Kentucky 67
• Princeton, New Jersey 66
• Manhattan, Kansas 65
• Las Vegas, Nevada 64
• Blacksburg, Virginia 63
• Detroit, Michigan 63
• Columbia, South Carolina 62
• Texarkana, Texas 61
• Wilmington, Delaware 60
• Aurora, Colorado 59
• Buffalo, New York 59
• Redwood City, California 59
• Tallahassee, Florida 59
• Toledo, Ohio 59
• Gainesville, Florida 58
• Lincoln, Nebraska 58
• New Haven, Connecticut 58
• Fremont, California 57
• Santa Monica, California 57
• Gaithersburg, Maryland 56
• Knoxville, Tennessee 56
• Menlo Park, California 56
• Harrisburg, Pennsylvania 54
• Jacksonville, Florida 54
• Lansing, Michigan 54
• Evanston, Illinois 53
• Ithaca, New York 53
• Columbia, Maryland 52
• Long Beach, California 51
• South San Francisco, California 51
• Carlsbad, California 50
• Springfield, Illinois 50