Startups in the United States

The Innovative EcoSystems registry lists 1,456 startups in the United States.

Startups are young companies building new products or business models.

The largest concentrations are in Cincinnati, Ohio (69), Boulder, Colorado (57) and Richmond, Virginia (52).

The United States scores 68.5 out of 100 on the IEPA (2024 edition), ranking 21 of 117 economies.

See the United States on the IEPA ↗

1,456 startups

• 1Logtech
  Startup · Westerville · 1logtech.com
• 2Build AI
  Startup · Overland Park · 2build.ai
• 34 Gigs
  Startup · Columbus · 34gigs.com
• 7Signal
  Startup · Independence · 7signal.com
• Abcon Therapeutics
  Startup · Cleveland · abcontx.com
• Abre
  Startup · Cincinnati · abre.com
• Absurd Snacks
  Startup · Richmond · absurdsnacks.com
• AccessVR (OrchestrateXR)
  Startup · Winchester · accessvr.com
• AcreShield
  Startup · Des Moines · acreshield.com
• ActionStreamer
  Startup · Cincinnati · actionstreamer.com
• ActivArmor
  Startup · Port St. Lucie · activarmor.com
• Adaptive Aerospace Group
  Startup · Hampton · adaptiveaero.com
• Advanced Aircraft Company
  Startup · Hampton · advancedaircraftcompany.com
• Advaray
  Startup · Charlottesville · advaray.com
• AeroApplied
  Startup · aeroapplied.com
• Agami Zero
  Startup · Colorado · agamizero.com
• AGarvey Engineering Solutions
  Startup · Xenia · agarveyllc.com
• Agile Ultrasonics
  Startup · Columbus · agileultrasonics.com
• Agiloop
  Startup · Palmer Lake · agiloop.ai
• Agri-Industrial Plastics
  Startup · Fairfield · innovationia.com
• Agricision
  Startup · Sedley · agricisioninc.com
• Agroptics
  Startup · agroptics.com
• AgroSpheres
  Startup · Charlottesville · agrospheres.com
• AI for the Rest of Us
  Startup · Denver · airestofus.com
• AIKOLO
  Startup · Delray Beach · aikolo.com
• AIR EV
  Startup · Indiantown · airev.aero
• Airtrek Robotics
  Startup · Cincinnati · airtrekrobotics.com
• Airway Therapeutics
  Startup · Atlanta · airwaytherapeutics.com
• Akron Innovations
  Startup · Akron · akroninnovations.com
• Albatross Golf
  Startup · Prairie Village · golftrk.com
• AlensiaXR
  Startup · Aurora · alensiaxr.com
• AlignAI
  Startup · Columbus · getalignai.com
• ALN Technology (SalesE)
  Startup · Virginia Beach · alntechnology.ai
• Alps Dx
  Startup · Richmond · alpsdx.com
• Alquist 3D
  Startup · Greeley · alquist3d.com
• Alta Resource Technologies
  Startup · Boulder · altatech.io
• Alterna
  Startup · Fort Collins · alterna.earth
• American Fertilizer
  Startup · Windsor · americanfertilizer.com
• AminoCloud
  Startup · Richmond · aminocloud.com
• Amoofy
  Startup · Denver · amoofy.com
• AMOR FELINE
  Startup · Ravenna · amorfeline.com
• AmpliFund
  Startup · Closed · amplifund.com
• Amruta
  Startup · Fredericksburg · amrutainc.com
• Analytical Insider
  Startup · Denver · analyticalinsider.ai
• Andon Bio
  Startup · Aurora · andon.bio
• AndrenaM
  Startup · Golden · andrenam.com
• Ansa Biotechnologies
  Startup · ansabio.com
• AOA Dx
  Startup · Denver · aoadx.com
• Aplos Data
  Startup · Columbus · aplosdata.com
• Apricity Robotics
  Startup · Dublin · apricity.ai
• Aqualung Therapeutics
  Startup · Jupiter · aqualungtherapeutics.com
• Ara Platforms
  Startup · ara.social
• ARCSys Technologies
  Startup · Virginia Beach · arcsystechnologies.com
• Arentha
  Startup · Colorado Springs · arentha.net
• Arkana Therapeutics
  Startup · Boulder · arkanatx.com
• AROPHA
  Startup · Cleveland · aropha.com
• Arrellio
  Startup · Columbus · arrellio.com
• Ascent Integrated Tech
  Startup · Chicago · ascentitech.com
• Ask Sage
  Startup · Closed · Arlington · asksage.ai
• AssureSync
  Startup · Chagrin Falls · assuresync.io
• AST2
  Startup · Youngstown · ast2.net
• Astraea
  Startup · Charlottesville · astraea.earth
• Asynt Solutions
  Startup · Columbus · asyntsolutions.com
• At Home Harmony
  Startup · Henrico · athomeharmony.com
• ATS Energy
  Startup · Loveland · ats.energy
• Attochron
  Startup · Lexington · attochron.com
• Audivi AI
  Startup · Milford · audiviai.com
• Augment Therapy
  Startup · Chagrin Falls · augmenttherapy.com
• Augur Technologies
  Startup · Boulder · wunderkind.co
• Autology
  Startup · Cincinnati · autology.bio
• Avant Genomics
  Startup · Charlottesville · avantgenomics.com
• AVEX
  Startup · Cedar Rapids · repour.com
• Aware Innovations
  Startup · West Carrollton · awareinnovations.com
• Axe.AI
  Startup · Dayton · axe.ai
• AxioSight
  Startup · Herndon · axiosight.com
• AxoNeural Therapeutics
  Startup · Cleveland · axoneuraltherapeutics.com
• Axuall
  Startup · Cleveland · axuall.com
• b-paid
  Startup · Columbus · b-paid.com
• BallotReady
  Startup · Chicago · ballotready.org
• Battle Sight Technologies
  Startup · Dayton · battlesighttech.com
• Battleface
  Startup · battleface.com
• Beacon
  Startup · Hilliard · beaconnection.com
• Benson
  Startup · meetbenson.com
• Bezlio
  Startup · Akron · bezlio.com
• Big Data in a Box
  Startup · Ames · bdibsolutions.com
• Biggie's Bakes
  Startup · Richmond · biggiesbakes.com
• Bio::Neos
  Startup · Coralville · bioneos.com
• BioChip Labs
  Startup · Cleveland · biochiplabs.com
• BIOHM Health
  Startup · Cleveland · biohmhealth.com
• BioMendics
  Startup · Rootstown · biomendics.com
• Bisc Therapeutics
  Startup · bisctherapeutics.com
• BK FastPass
  Startup · Boulder · bkfastpass.com
• blooom
  Startup · Leawood · blooom.com
• Blue Frontier
  Startup · Boca Raton · blue-frontier.com
• BlueprintNAV
  Startup · West Des Moines · blueprintnav.com
• BluJaket
  Startup · Davenport · blujaket.com
• BNNT Materials
  Startup · Newport News · bnnt.com
• Bold Penguin
  Startup · Columbus · boldpenguin.com
• BOPA Precision Agriculture
  Startup · La Junta · barnowlag.com
• Brain-CA Technologies
  Startup · Cincinnati · brain-ca.com
• BrainBox Solutions
  Startup · Richmond · brainboxinc.com
• Branch Insurance
  Startup · Columbus · ourbranch.com
• Brandefy
  Startup · Richmond · brandefyskin.com
• Bravura-AI
  Startup · Jupiter · bravura-ai.com
• Breadtopia
  Startup · Fairfield · breadtopia.com
• BriefCatch
  Startup · Arlington · briefcatch.com
• Brightn
  Startup · Cedar Rapids · brightn.app
• Buddy
  Startup · Richmond · buddy.insure
• BuildFactory
  Startup · Cedar Rapids · buildfactory.io
• BulkSource
  Startup · Greenwood Village · bulksource.com
• BundleIQ
  Startup · West Palm Beach · bundleiq.com
• Bungii
  Startup · Overland Park · bungii.com
• Burnshire HydroElectric
  Startup · Star Tannery · burnshirehydro.com
• Caddis
  Startup · Hilliard · caddistech.com
• Caju
  Startup · Charlottesville · caju.ai
• CAL Analytics
  Startup · Beavercreek · calanalytics.com
• Canvas Technology
  Startup · Boulder · canvas.technology
• Carecubes
  Startup · Arlington · carecubes.com
• Career Town Network
  Startup · Columbus · careertown.net
• CarePilot
  Startup · Leawood · carepilot.com

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Cities

• Startups in Cincinnati, Ohio 69
• Startups in Boulder, Colorado 57
• Startups in Richmond, Virginia 52
• Startups in Denver, Colorado 50
• Startups in Columbus, Ohio 47
• Startups in Cleveland, Ohio 42
• Startups in Ames, Iowa 40
• Startups in Tulsa, Oklahoma 33
• Startups in Chicago, Illinois 32
• Startups in Des Moines, Iowa 31
• Startups in Oklahoma City, Oklahoma 29
• Startups in Iowa City, Iowa 28
• Startups in Norman, Oklahoma 24
• Startups in Boca Raton, Florida 22
• Startups in Charlottesville, Virginia 22
• Startups in Lawrence, Kansas 19
• Startups in Overland Park, Kansas 18
• Startups in Cedar Rapids, Iowa 16
• Startups in Coralville, Iowa 16
• Startups in Dayton, Ohio 16
• Startups in Fort Collins, Colorado 16
• Startups in Wichita, Kansas 15
• Startups in Blacksburg, Virginia 14
• Startups in Alexandria, Virginia 13
• Startups in Norfolk, Virginia 12
• Startups in Roanoke, Virginia 12
• Startups in Toledo, Ohio 12
• Startups in West Palm Beach, Florida 11
• Startups in Arlington, Virginia 10
• Startups in Aurora, Colorado 10
• Startups in Colorado Springs, Colorado 10
• Startups in Golden, Colorado 9
• Startups in Hampton, Virginia 9
• Startups in Greeley, Colorado 8
• Startups in McLean, Virginia 8
• Startups in Akron, Ohio 7
• Startups in Champaign, Illinois 7
• Startups in Dublin, Ohio 7
• Startups in Erie, Colorado 7
• Startups in Longmont, Colorado 7
• Startups in Reston, Virginia 7
• Startups in West Des Moines, Iowa 7
• Startups in Cedar Falls, Iowa 6
• Startups in Fairfield, Iowa 6
• Startups in Jupiter, Florida 6
• Startups in Leawood, Kansas 6
• Startups in Lenexa, Kansas 6
• Startups in Broomfield, Colorado 5
• Startups in Chagrin Falls, Ohio 5
• Startups in Davenport, Iowa 5
• Startups in Delray Beach, Florida 5
• Startups in Hilliard, Ohio 5
• Startups in Lafayette, Colorado 5
• Startups in Olathe, Kansas 5
• Startups in Palm Beach Gardens, Florida 5
• Startups in Ankeny, Iowa 4
• Startups in Clive, Iowa 4
• Startups in Durango, Colorado 4
• Startups in Edmond, Oklahoma 4
• Startups in Englewood, Colorado 4
• Startups in Henrico, Virginia 4
• Startups in Kansas City, Kansas 4
• Startups in Littleton, Colorado 4
• Startups in Manhattan, Kansas 4
• Startups in Mason, Ohio 4
• Startups in Sioux City, Iowa 4
• Startups in Virginia Beach, Virginia 4
• Startups in Youngstown, Ohio 4
• Startups in Buena Vista, Colorado 3
• Startups in Centennial, Colorado 3
• Startups in Council Bluffs, Iowa 3
• Startups in Fairfax, Virginia 3
• Startups in Grand Junction, Colorado 3
• Startups in Greenwood Village, Colorado 3
• Startups in Herndon, Virginia 3
• Startups in Loveland, Colorado 3
• Startups in Milford, Ohio 3
• Startups in Newport News, Virginia 3
• Startups in Prairie Village, Kansas 3
• Startups in Topeka, Kansas 3
• Startups in Urbandale, Iowa 3
• Startups in Windsor, Colorado 3
• Startups in Xenia, Ohio 3