United States innovation ecosystem

The Innovative EcoSystems registry lists 40,532 innovation ecosystem organizations in the United States, including 10,487 corporate R&D centers, 10,299 research organizations and 6,125 universities and research institutes.

The largest concentrations are in New York, New York (1,450), Washington, DC (1,418) and Chicago, Illinois (732).

The United States scores 68.5 out of 100 on the IEPA (2024 edition), ranking 21 of 117 economies.

See the United States on the IEPA ↗

40,532 organizations

• Sierra View Medical Center
  Health research · Porterville · sierra-view.com
• Siga Technologies (United States)
  Corporate R&D · New York · siga.com
• SightGlass Vision, Inc. (United States)
  Corporate R&D · Dallas · sightglassvision.com
• SightLife
  Research organization · Seattle · sightlife.org
• Sigma Designs (United States)
  Corporate R&D · Fremont · sigmadesigns.com
• Sigma Genosys (United States)
  Corporate R&D · The Woodlands · genosys.com
• Sigma Labs (United States)
  Corporate R&D · Santa Fe · sigmalabsinc.com
• Sigma Space (United States)
  Corporate R&D · Lanham · sigmaspace.com
• Sigma Technologies (United States)
  Corporate R&D · Tucson · sigma-technologies.com
• Sigma Technologies International (United States)
  Corporate R&D · Closed · Tucson · sigmalabs.com
• Sigma Theta Tau International
  Health research · Indianapolis · nursingsociety.org
• Sigma Xi
  Research organization · Research Triangle Park · sigmaxi.org
• Sigma-Aldrich (United States)
  Corporate R&D · Dormant · St Louis · sigmaaldrich.com
• Sigma-K (United States)
  Corporate R&D · Durham · sigma-k.com
• Sigma-Tau Pharmaceuticals (United States)
  Corporate R&D · Gaithersburg · sigmatau.com
• Sigma³ (United States)
  Corporate R&D · Houston · sigmacubed.com
• Sigmatech (United States)
  Corporate R&D · Huntsville · sigmatech.com
• Sigmovir Biosystems (United States)
  Corporate R&D · Rockville · sigmovir.com
• Sign Media (United States)
  Corporate R&D · Burtonsville · signmedia.com
• SignaBlok (United States)
  Corporate R&D · Shrewsbury · signablok.com
• Signal Genetics (United States)
  Corporate R&D · Carlsbad · signalgenetics.com
• Signal Processing (United States)
  Corporate R&D · Rockville · signalpro.net
• Signal Systems Corporation (United States)
  Corporate R&D · Maryland City · signalsystemscorp.com
• SignalRx Pharmaceuticals (United States)
  Corporate R&D · San Diego · signalrx.com
• Signals Analytics (United States)
  Corporate R&D · New York · signals-analytics.com
• Signature Analytics (United States)
  Corporate R&D · San Diego · signatureanalytics.com
• Signature Healthcare Brockton Hospital
  Health research · Brockton · signature-healthcare.org
• Signature Research (United States)
  Corporate R&D · Houghton · signatureresearchinc.com
• Signature Research Institute
  Research organization · Louisville · srihealth.org
• Signosis (United States)
  Corporate R&D · Santa Clara · signosisinc.com
• SignPath Pharma (United States)
  Corporate R&D · Sandy · signpathpharma.com
• Signum Biosciences (United States)
  Corporate R&D · Boulder · signumbiosciences.com
• Sigray (United States)
  Corporate R&D · Concord · sigray.com
• SiILion (United states)
  Corporate R&D · Broomfield · siilion.com
• Sikh Foundation
  Research organization · Palo Alto · sikhfoundation.org
• Sikorsky Aircraft Corporation (United States)
  Corporate R&D · Huntsville · sikorsky.com
• SIL International
  Research organization · Dallas · sil.org
• Sila Nanotechnologies (United States)
  Corporate R&D · Alameda · silanano.com
• SilaGene (United States)
  Corporate R&D · New Brunswick · silagene.com
• Silatronix (United States)
  Corporate R&D · Madison · silatronix.com
• SilBiotech (United States)
  Corporate R&D · Gaithersburg · silbiotech.com
• SilcsBio (United States)
  Corporate R&D · Baltimore · silcsbio.com
• Silence Therapeutics (United States)
  Corporate R&D · Palo Alto · silence-therapeutics.com
• Silent Push
  Startup · Reston · silentpush.com
• Silent Spring Institute
  Research organization · Newton · silentspring.org
• Silicon Audio (United States)
  Corporate R&D · Austin · siaudio.com
• Silicon Chemical (United States)
  Corporate R&D · Washougal · siliconchemical.com
• Silicon Designs (United States)
  Corporate R&D · Kirkland · silicondesigns.com
• Silicon Flatirons
  Research organization · Boulder · siliconflatirons.org
• Silicon Graphics International (United States)
  Corporate R&D · Closed · Milpitas · sgi.com
• Silicon Labs (United States)
  Corporate R&D · Austin · silabs.com
• Silicon Micro Display (United States)
  Corporate R&D · Novato · siliconmicrodisplay.com
• Silicon Mitus (United States)
  Corporate R&D · Cupertino · siliconmitus.com
• Silicon Power Corporation (United States)
  Corporate R&D · Malvern · siliconpowercorporation.com
• Silicon Technologies (United States)
  Corporate R&D · Millcreek · silicontechnologiesinc.com
• Silicon Therapeutics (United States)
  Corporate R&D · Boston · silicontx.com
• Silicon Valley Bank (a division of First Citizens Bank)
  Investor or fund · Virginia office · svb.com
• Silicon Valley Community Foundation
  Research organization · Mountain View · siliconvalleycf.org
• Silicon Valley Education Foundation
  Research organization · San Jose · svefoundation.org
• Silicon Valley Independent Living Center
  Research organization · San Jose · svilc.org
• Silicon Valley University
  University or research institute · San Jose · svuca.edu
• Silk Road Medical (United States)
  Corporate R&D · Sunnyvale · silkroadmed.com
• Silk Technologies (United States)
  Corporate R&D · Plymouth · silk-tech.com
• SillaJen (United States)
  Corporate R&D · San Francisco · sillajen.com
• Silsbee Independent School District
  University or research institute · Silsbee · silsbeeisd.org
• Silvaco Group, Inc. (United States)
  Corporate R&D · Santa Clara · silvaco.com
• Silver Buffalo Consulting
  University or research institute · Richmond · silverbuffalo.org
• Silver Bullet Solutions (United States)
  Corporate R&D · Arlington · silverbulletinc.com
• Silver Cross Hospital
  Health research · Joliet · silvercross.org
• Silver Lake College
  University or research institute · Manitowoc · sl.edu
• Silver Lake Research (United States)
  Corporate R&D · Monrovia · silverlakeresearch.com
• Silverchair Information Systems (United States)
  Corporate R&D · Charlottesville · silverchair.com
• Silverside Detectors (United States)
  Corporate R&D · Cambridge · sside.co
• Silverstein Institute
  University or research institute · Sarasota · earsinus.com
• Silverton Hospital
  Health research · Silverton · silvertonhealth.org
• Silvestrum Climate Associates
  Research organization · San Francisco · silvestrum.com
• Silvus Technologies (United States)
  Corporate R&D · Los Angeles · silvustechnologies.com
• SIM*VIVO (United States)
  Corporate R&D · New York · sim-vivo.com
• Simbex (United States)
  Corporate R&D · Lebanon · simbex.com
• SimBiotic Software (United States)
  Corporate R&D · Ithaca · simbio.com
• Simerics (United States)
  Corporate R&D · Bellevue · simerics.com
• Simetri (United States)
  Corporate R&D · Winter Park · simetri.us
• Simha Foundation
  Research organization · Washington · simha.org
• Simmaron Research
  Research organization · Incline Village · simmaronresearch.com
• SIMmersion (United States)
  Corporate R&D · Columbia · simmersion.com
• Simmetrix (United States)
  Corporate R&D · Saratoga Springs · simmetrix.com
• Simmons College of Kentucky
  University or research institute · Louisville · simmonscollegeky.edu
• Simmons Family Foundation
  Research organization · Farmington · simmonsfoundation.org
• Simmons Perrine
  Company · Cedar Rapids · simmonsperrine.com
• Simmons University
  University or research institute · Boston · simmons.edu
• Simmtec (United States)
  Corporate R&D · Fremont · simmtec.com
• Simons Center for Geometry and Physics
  University or research institute · Stony Brook · scgp.stonybrook.edu
• Simons Foundation
  Research organization · New York · simonsfoundation.org
• Simonsen Laboratories
  Corporate R&D · Gilroy · simlab.com
• Simphotek (United States)
  Corporate R&D · Newark · simphotek.net
• Simple Mills
  Company · Chicago · simplemills.com
• Simple Startup
  Company · Boulder · simplestartup.com
• Simplex Manufacturing (United States)
  Corporate R&D · Portland · simplex.aero
• Simplify Medical (United States)
  Corporate R&D · Sunnyvale · simplifymedical.com
• Simplot (United States)
  Corporate R&D · Boise · simplot.com
• SiMPore (United States)
  Corporate R&D · Rochester · simpore.com
• Simpson College
  University or research institute · Indianola · simpson.edu
• Simpson Strong-Tie (United States)
  Corporate R&D · Pleasanton · strongtie.com
• Simpson University
  University or research institute · Redding · simpsonu.edu
• Simpson Weather Associates (United States)
  Corporate R&D · Charlottesville · swa.com
• SimQuest (United States)
  Corporate R&D · Annapolis · simquest.com
• Sims Brothers (United States)
  Corporate R&D · Union Springs · simsbros.com
• Simulation Technologies (United States)
  Corporate R&D · Huntsville · simtechinc.com
• Simulations Plus (United States)
  Corporate R&D · Lancaster · simulations-plus.com
• SimulConsult
  Corporate R&D · Boston · simulconsult.com
• SimulTel (United States)
  Corporate R&D · New York · simultel.com
• SimulTOF Systems (United States)
  Corporate R&D · Marlborough · simultof.com
• SimuTech Group (United States)
  Corporate R&D · Atlanta · simutechgroup.com
• SimVentions (United States)
  Corporate R&D · Fredericksburg · simventions.net
• SimWright (United States)
  Corporate R&D · Navarre · simwright.com
• Sinai Grace Hospital
  Health research · Detroit · sinaigrace.org
• Sinai Health System
  Health research · Chicago · sinai.org
• Sinai Hospital
  Health research · Baltimore · lifebridgehealth.org
• Sinclair Community College
  University or research institute · Dayton · sinclair.edu
• Sinclair Community College Fab Lab
  Fab lab or makerspace · Dayton · sinclair.edu

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Categories

• Corporate R&D centers in the United States 10,487
• Research organizations in the United States 10,299
• Universities and research institutes in the United States 6,125
• Health research organizations in the United States 4,117
• Government and public bodies in the United States 2,323
• Other organizations in the United States 1,506
• Startups in the United States 1,456
• Companies in the United States 898
• Programs in the United States 707
• Investors and funds in the United States 656
• Networks and associations in the United States 640
• Science and technology parks in the United States 539
• Fab labs and makerspaces in the United States 352
• Innovation hubs in the United States 133
• Accelerators in the United States 116
• Incubators in the United States 110
• Colleges and training providers in the United States 66

Cities

• New York, New York 1,450
• Washington, DC 1,418
• Chicago, Illinois 732
• San Diego, California 485
• Boston, Massachusetts 470
• San Francisco, California 467
• Denver, Colorado 441
• Los Angeles, California 398
• Seattle, Washington 386
• Columbus, Ohio 324
• Boulder, Colorado 323
• Atlanta, Georgia 304
• Houston, Texas 302
• Philadelphia, Pennsylvania 299
• Cambridge, Massachusetts 295
• Cleveland, Ohio 287
• Arlington, Virginia 275
• Cincinnati, Ohio 274
• Austin, Texas 272
• Des Moines, Iowa 237
• Richmond, Virginia 236
• Baltimore, Maryland 225
• Pittsburgh, Pennsylvania 219
• Oklahoma City, Oklahoma 218
• Durham, North Carolina 201
• Portland, Oregon 190
• Dallas, Texas 174
• Madison, Wisconsin 172
• Minneapolis, Minnesota 170
• Bethesda, Maryland 168
• St Louis, Missouri 168
• Oakland, California 167
• Tulsa, Oklahoma 166
• Alexandria, Virginia 162
• Indianapolis, Indiana 162
• Rockville, Maryland 161
• Berkeley, California 159
• Ann Arbor, Michigan 154
• Salt Lake City, Utah 154
• Charlottesville, Virginia 152
• Tucson, Arizona 148
• Wichita, Kansas 148
• San Antonio, Texas 141
• Boca Raton, Florida 140
• Albuquerque, New Mexico 137
• San Jose, California 135
• Miami, Florida 134
• Raleigh, North Carolina 133
• West Palm Beach, Florida 131
• Phoenix, Arizona 128
• Ames, Iowa 125
• Dayton, Ohio 125
• Saint Paul, Minnesota 124
• Sacramento, California 123
• Silver Spring, Maryland 121
• Honolulu, Hawaii 119
• Milwaukee, Wisconsin 112
• Colorado Springs, Colorado 111
• Palo Alto, California 108
• Nashville, Tennessee 107
• Brooklyn, New York 106
• Iowa City, Iowa 100
• Irvine, California 97
• Orlando, Florida 88
• Albany, New York 86
• Champaign, Illinois 86
• Fort Collins, Colorado 86
• Reston, Virginia 86
• Waltham, Massachusetts 86
• Anchorage, Alaska 85
• Greeley, Colorado 85
• Lawrence, Kansas 85
• Louisville, Kentucky 85
• Norfolk, Virginia 85
• Tampa, Florida 85
• Charlotte, North Carolina 83
• Norman, Oklahoma 83
• Kansas City, Missouri 82
• Mountain View, California 81
• New Orleans, Louisiana 81
• Fairfax, Virginia 80
• Huntsville, Alabama 79
• Cedar Rapids, Iowa 78
• Overland Park, Kansas 78
• Santa Fe, New Mexico 77
• Topeka, Kansas 77
• Sunnyvale, California 76
• La Jolla, California 75
• Memphis, Tennessee 74
• McLean, Virginia 73
• Omaha, Nebraska 73
• Pasadena, California 73
• Santa Barbara, California 73
• Santa Clara, California 73
• Akron, Ohio 72
• Baton Rouge, Louisiana 72
• Birmingham, Alabama 72
• Rochester, New York 72
• Little Rock, Arkansas 70
• Hartford, Connecticut 69
• Providence, Rhode Island 69
• Lexington, Kentucky 67
• Princeton, New Jersey 66
• Manhattan, Kansas 65
• Las Vegas, Nevada 64
• Blacksburg, Virginia 63
• Detroit, Michigan 63
• Columbia, South Carolina 62
• Texarkana, Texas 61
• Wilmington, Delaware 60
• Aurora, Colorado 59
• Buffalo, New York 59
• Redwood City, California 59
• Tallahassee, Florida 59
• Toledo, Ohio 59
• Gainesville, Florida 58
• Lincoln, Nebraska 58
• New Haven, Connecticut 58
• Fremont, California 57
• Santa Monica, California 57
• Gaithersburg, Maryland 56
• Knoxville, Tennessee 56
• Menlo Park, California 56
• Harrisburg, Pennsylvania 54
• Jacksonville, Florida 54
• Lansing, Michigan 54
• Evanston, Illinois 53
• Ithaca, New York 53
• Columbia, Maryland 52
• Long Beach, California 51
• South San Francisco, California 51
• Carlsbad, California 50
• Springfield, Illinois 50