Startups in the United States

The Innovative EcoSystems registry lists 1,456 startups in the United States.

Startups are young companies building new products or business models.

The largest concentrations are in Cincinnati, Ohio (69), Boulder, Colorado (57) and Richmond, Virginia (52).

The United States scores 68.5 out of 100 on the IEPA (2024 edition), ranking 21 of 117 economies.

See the United States on the IEPA ↗

1,456 startups

• PrairieFood
  Startup · Lawrence · prairiefood.com
• PrairieLearn
  Startup · Champaign · prairielearn.com
• Presaj
  Startup · Cedar Rapids · presaj.ai
• Prescribe FIT
  Startup · Columbus · prescribefit.com
• Pretred
  Startup · Aurora · pretred.com
• Prince Biotech
  Startup · Mason · princebiotech.com
• Profluent
  Startup · profluent.bio
• Proov
  Startup · Erie · proovtest.com
• Pyrone Systems
  Startup · Ames · pyronesys.com
• Qentoros
  Startup · Blacksburg · qentoros.com
• Qlutch QMS
  Startup · Roanoke · qlutchqms.com
• Quadratic
  Startup · Boulder · quadratichq.com
• Quantum Lending Solutions
  Startup · Reston · quantumlendingsolutions.com
• Quartermaster AI
  Startup · Arlington · quartermaster.us
• R3 Digital Sciences
  Startup · Blacksburg · r3-ds.com
• Radiant Robotics
  Startup · Oberlin · radiantrobotics.ai
• RADICL
  Startup · Boulder · radicl.com
• RAIsonance
  Startup · Greenwood Village · raisonance.ai
• Rametrix Technologies
  Startup · Blacksburg · rametrixtech.com
• Range
  Startup · McLean · range.com
• RangersAI
  Startup · Boca Raton · rangersai.com
• Rantizo
  Startup · Iowa City · rantizo.com
• Rare Earth Technologies, Inc. (RETi)
  Startup · Cincinnati · rareearth.tech
• Ravee Optics
  Startup · Dayton · raveeoptics.com
• Raynmaker
  Startup · Denver · raynmaker.ai
• Ready Robotics
  Startup · ready-robotics.com
• ReadySet Surgical
  Startup · Cleveland · readysetsurgical.com
• Reality Wave
  Startup · Coralville · reviewer.realitywave.ai
• Rebulk
  Startup · Olathe · rebulk.com
• Reconstruct
  Startup · Champaign · reconstructinc.com
• Recruiter-in-the-Loop
  Startup · West Chester Township · recruiterintheloop.ai
• Red Sky Health
  Startup · Solon · redskyhealth.com
• Redactable
  Startup · Norfolk · redactable.com
• Redi Health
  Startup · Columbus · redi.health
• Reef Arches
  Startup · West Palm Beach · reefarches.com
• Reelist
  Startup · Norfolk · 757collab.org
• ReEnvision Ag
  Startup · Nora Springs · reenvisionag.com
• Regelife
  Startup · Boulder · regelife.bio
• REI Hub
  Startup · Closed · Richmond · reihub.net
• Remission Medical
  Startup · Richmond · remissionmedical.com
• Renalis
  Startup · Cleveland · renalis.health
• Repaint Studios
  Startup · Iowa Falls · repaintstudios.com
• Richbrau Brewing
  Startup · Richmond · richbraubrewing.com
• Rilian
  Startup · McLean · rilian.com
• RiPSIM Technologies
  Startup · Ashburn · ripsim.com
• Risk Aperture
  Startup · Blacksburg · risk-aperture.com
• RoadPrintz
  Startup · Cleveland · roadprintz.com
• Roboflow
  Startup · Des Moines · roboflow.com
• Ronawk
  Startup · Olathe · ronawk.com
• Rooted Robotics
  Startup · Boulder · rootedrobotics.com
• Routh Systems
  Startup · Fort Collins · routhsystems.com
• Rowe Casa Organics
  Startup · New Boston · rowecasaorganics.com
• Rune Technologies
  Startup · Arlington · runetech.co
• RV Fiber
  Startup · Greeley · rvfiber.net
• RV Help
  Startup · Montrose · rvhelp.com
• RWX
  Startup · Columbus · rev1ventures.com
• Ryzing Technologies
  Startup · Staunton · ryzingtech.com
• S1P Therapeutics
  Startup · Blacksburg · s1ptx.com
• S4 Medical
  Startup · Cleveland · s4medical.com
• S4 Mobile Laboratories
  Startup · Akron · s4laboratories.com
• Sachi Bioworks
  Startup · Erie · sachibio.com
• SAFI-Tech
  Startup · Ames · safi-tech.com
• Salsas Don Sebastian
  Startup · Midlothian · salsasdonsebastian.com
• Saporo
  Startup · Columbus · saporo.io
• SAPRA Biomedicals
  Startup · Blacksburg · saprabiomedicals.com
• Sartography
  Startup · Staunton · sartography.com
• Saturn Sports
  Startup · Cincinnati · saturnsportsllc.com
• Scanlily
  Startup · Blacksburg · scanlily.com
• SCATR
  Startup · Cleveland · scatrcorp.ai
• Scenario Trainer
  Startup · Mayfield Heights · scenariotrainer.com
• Schematic
  Startup · Boulder · schematichq.com
• Sci-Lume Labs
  Startup · Oklahoma City · sci-lumelabs.com
• Scout
  Startup · Overland Park · scoutapp.vet
• Scout Space
  Startup · Reston · scout.space
• Searchcraft
  Startup · Denver · searchcraft.io
• Seauciel
  Startup · Mentor · seauciel.com
• SeedMetrics
  Startup · Richmond · seedmetrics.io
• Segtax
  Startup · Richmond · seg.tax
• SEMPRE
  Startup · Colorado Springs · sempre.ai
• Sensulin
  Startup · Oklahoma City · sensulin.com
• Sentinel Robotic Solutions
  Startup · Wallops Island · srsgrp.com
• Sentire Medical Systems
  Startup · Palm Beach Gardens · sentiremedical.com
• Sevelyn
  Startup · Clive · sevelyn.com
• Sewn 2 Dance
  Startup · Sioux City · sewn2dance.com
• Sherah
  Startup · Richmond · mysherah.com
• ShotTracker
  Startup · Merriam · shottracker.com
• Silent Push
  Startup · Reston · silentpush.com
• Skillframe
  Startup · Mentor · skillframe.ai
• Skuld
  Startup · Piqua · skuldllc.com
• Skyhook Solar
  Startup · Grand Junction · skyhooksolar.com
• Skytree Scientific
  Startup · Asheville · skytreescientific.ai
• SkyWind Solutions
  Startup · Boca Raton · skywindsolutions.com
• SMART-LE Medical/Nursing VR
  Startup · Cleveland · smartlevr.com
• SmartAuger Technologies
  Startup · Akron · smart-auger.com
• SMRxT
  Startup · Overland Park · smrxt.com
• Socially Determined
  Startup · sociallydetermined.com
• Society Brands
  Startup · Canton · societybrands.com
• SOFTwarfare
  Startup · Prairie Village · softwarfare.com
• sol
  Startup · Commerce City · solpbc.org
• Sola
  Startup · Atlanta · solainsurance.com
• SoLo Funds
  Startup · Cincinnati · solofunds.com
• SourceEazy
  Startup · Des Moines · sourceeazy.com
• Spendr
  Startup · Cincinnati · spendr.com
• SpiderOak
  Startup · Overland Park · spideroak.com
• Spines
  Startup · Boynton Beach · spines.com
• Splice
  Startup · Norfolk · splice-it.com
• Spline
  Startup · Reston · spline.design
• Springbok Analytics
  Startup · Charlottesville · springbokanalytics.com
• Stack Health
  Startup · Columbus · stackhealth.com
• StackHawk
  Startup · Colorado · stackhawk.com
• Staffing Engine
  Startup · Boulder · staffingengine.ai
• Standard Bariatrics
  Startup · Closed · Cincinnati · standardbariatrics.com
• Steel Therapeutics
  Startup · Iowa City · steeltherapeutics.com
• Storypie
  Startup · Cleveland · mystorypie.com
• Straddle
  Startup · Broomfield · straddle.com
• Strangpresse
  Startup · Warren · strangpresse.com
• Stratafolio
  Startup · Cedar Rapids · stratafolio.com
• Structurely
  Startup · Aspen · structurely.com
• Suite Studios
  Startup · Boulder · suitestudios.io
• SupplyNow
  Startup · Cleveland · supplynow.io

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Cities

• Startups in Cincinnati, Ohio 69
• Startups in Boulder, Colorado 57
• Startups in Richmond, Virginia 52
• Startups in Denver, Colorado 50
• Startups in Columbus, Ohio 47
• Startups in Cleveland, Ohio 42
• Startups in Ames, Iowa 40
• Startups in Tulsa, Oklahoma 33
• Startups in Chicago, Illinois 32
• Startups in Des Moines, Iowa 31
• Startups in Oklahoma City, Oklahoma 29
• Startups in Iowa City, Iowa 28
• Startups in Norman, Oklahoma 24
• Startups in Boca Raton, Florida 22
• Startups in Charlottesville, Virginia 22
• Startups in Lawrence, Kansas 19
• Startups in Overland Park, Kansas 18
• Startups in Cedar Rapids, Iowa 16
• Startups in Coralville, Iowa 16
• Startups in Dayton, Ohio 16
• Startups in Fort Collins, Colorado 16
• Startups in Wichita, Kansas 15
• Startups in Blacksburg, Virginia 14
• Startups in Alexandria, Virginia 13
• Startups in Norfolk, Virginia 12
• Startups in Roanoke, Virginia 12
• Startups in Toledo, Ohio 12
• Startups in West Palm Beach, Florida 11
• Startups in Arlington, Virginia 10
• Startups in Aurora, Colorado 10
• Startups in Colorado Springs, Colorado 10
• Startups in Golden, Colorado 9
• Startups in Hampton, Virginia 9
• Startups in Greeley, Colorado 8
• Startups in McLean, Virginia 8
• Startups in Akron, Ohio 7
• Startups in Champaign, Illinois 7
• Startups in Dublin, Ohio 7
• Startups in Erie, Colorado 7
• Startups in Longmont, Colorado 7
• Startups in Reston, Virginia 7
• Startups in West Des Moines, Iowa 7
• Startups in Cedar Falls, Iowa 6
• Startups in Fairfield, Iowa 6
• Startups in Jupiter, Florida 6
• Startups in Leawood, Kansas 6
• Startups in Lenexa, Kansas 6
• Startups in Broomfield, Colorado 5
• Startups in Chagrin Falls, Ohio 5
• Startups in Davenport, Iowa 5
• Startups in Delray Beach, Florida 5
• Startups in Hilliard, Ohio 5
• Startups in Lafayette, Colorado 5
• Startups in Olathe, Kansas 5
• Startups in Palm Beach Gardens, Florida 5
• Startups in Ankeny, Iowa 4
• Startups in Clive, Iowa 4
• Startups in Durango, Colorado 4
• Startups in Edmond, Oklahoma 4
• Startups in Englewood, Colorado 4
• Startups in Henrico, Virginia 4
• Startups in Kansas City, Kansas 4
• Startups in Littleton, Colorado 4
• Startups in Manhattan, Kansas 4
• Startups in Mason, Ohio 4
• Startups in Sioux City, Iowa 4
• Startups in Virginia Beach, Virginia 4
• Startups in Youngstown, Ohio 4
• Startups in Buena Vista, Colorado 3
• Startups in Centennial, Colorado 3
• Startups in Council Bluffs, Iowa 3
• Startups in Fairfax, Virginia 3
• Startups in Grand Junction, Colorado 3
• Startups in Greenwood Village, Colorado 3
• Startups in Herndon, Virginia 3
• Startups in Loveland, Colorado 3
• Startups in Milford, Ohio 3
• Startups in Newport News, Virginia 3
• Startups in Prairie Village, Kansas 3
• Startups in Topeka, Kansas 3
• Startups in Urbandale, Iowa 3
• Startups in Windsor, Colorado 3
• Startups in Xenia, Ohio 3