Startups in the United States

The Innovative EcoSystems registry lists 1,456 startups in the United States.

Startups are young companies building new products or business models.

The largest concentrations are in Cincinnati, Ohio (69), Boulder, Colorado (57) and Richmond, Virginia (52).

The United States scores 68.5 out of 100 on the IEPA (2024 edition), ranking 21 of 117 economies.

See the United States on the IEPA ↗

1,456 startups

• LendingStandard
  Startup · Kansas City · lendingstandard.com
• LexAxiom
  Startup · Colorado Springs · lexaxiom.com
• Lightship
  Startup · Broomfield · lightshiprv.com
• Linebird
  Startup · Ashland · linebird.net
• Liquet Medical
  Startup · Glen Allen · liquetmedical.com
• Lithios
  Startup · Boston · lithios.com
• Liti Holographics
  Startup · litiholo.com
• LittleSeed
  Startup · Hilliard · littleseed.io
• LODAS Markets
  Startup · Overland Park · lodasmarkets.com
• LogiCall Health
  Startup · Greenwood Village · logicallhealth.com
• Loom Security
  Startup · Lawrence · loomsecurity.com
• Losant
  Startup · Closed · Cincinnati · losant.com
• Love Lifesciences
  Startup · Lawrence · lovelifesciences.com
• LSF Medical Solutions
  Startup · Iowa City · lsfmedicalsolutions.com
• LuminAID
  Startup · Chicago · luminaidlab.com
• Luminoah
  Startup · Charlottesville · 757collab.org
• Lux Aeterna
  Startup · Denver · luxaeterna.com
• Lux Blox
  Startup · Peoria · luxblox.com
• Lytos Technologies
  Startup · Waynesboro · lytostech.com
• MākuSafe
  Startup · West Des Moines · makusafe.com
• Mana Battery
  Startup · Denver · manabattery.com
• Manifest Technologies
  Startup · Boulder · manifest.tech
• Maybell Quantum
  Startup · Denver · maybellquantum.com
• Maybell Quantum Industries
  Startup · Denver · maybellquantum.com
• MedaSync
  Startup · Cleveland · medasync.com
• MedCurate
  Startup · medcurate.com
• Medentum Innovations
  Startup · Clintwood · medentum.com
• Medical Predictive Science
  Startup · Charlottesville · heroscore.com
• MediView XR
  Startup · Cleveland · mediview.com
• Memry
  Startup · Columbus · memryhealth.com
• Meshcomm Engineering
  Startup · Loveland · meshcommengineering.com
• MetaMol
  Startup · Milford · metamol.com
• Micro Harmonics
  Startup · Fincastle · microharmonics.com
• Micruity
  Startup · Sacramento · micruity.com
• Miles Labs
  Startup · Denver · mileslabs.com
• milkmade
  Startup · milkmade.co
• MintCover
  Startup · Woodstock · mintcover.net
• MLNavigator
  Startup · Wichita · mlnavigator.com
• Mobius Materials
  Startup · Richmond · mobiusmaterials.com
• Mod Advisor
  Startup · Des Moines · modadvisor.com
• MOVA Technologies
  Startup · Pulaski · movatechnologies.com
• Mulongo
  Startup · Denver · mulongo.com
• MuReva Phototherapy
  Startup · Brecksville · murevapt.com
• My One Medical Source
  Startup · Westlake · myonemedicalsource.com
• Myosin Therapeutics
  Startup · Jupiter · myosintherapeutics.com
• Nano Fixation
  Startup · Edwards · nanofixation.com
• Narro Trucks
  Startup · Dublin · narrotrucks.com
• Nasoni
  Startup · Suffolk · nasoni.com
• Native AI
  Startup · Cincinnati · gonative.ai
• Navidence
  Startup · Aurora · navidence.com
• NeoIndicate
  Startup · Wellington · neoindicate.com
• NeoProteomics
  Startup · Cleveland · neoproteomics.net
• Nestease
  Startup · Glen Allen · nestease.com
• Netarus
  Startup · Norfolk · netarus.com
• Network Perception
  Startup · Chicago · network-perception.com
• NeuroPred
  Startup · Coralville · neuropred.com
• NeuroTherapia
  Startup · Gates Mills · neurotherapia.com
• NeutraNarc
  Startup · Cincinnati · neutranarc.com
• Nexxt Medtech
  Startup · Lakewood · nexxtmedtech.com
• Niobium
  Startup · Dayton · niobium.co
• Niobium Microsystems
  Startup · Dayton · niobiummicrosystems.com
• Nitride Global
  Startup · Wichita · nitrideglobal.com
• Northslope
  Startup · Denver · northslope.com
• Notion (Loop Labs)
  Startup · Denver · getnotion.com
• Novel Capital
  Startup · Overland Park · novelcapital.com
• Nymbl
  Startup · Dublin · nymbl.healthcare
• Nymbl Systems
  Startup · Dublin · nymblsystems.com
• OAVAO Technologies
  Startup · Ames · oavaotech.com
• Objective Ed
  Startup · Wellington · objectiveed.com
• OccasionGenius
  Startup · Closed · Richmond · occasiongenius.com
• Octet Scientific
  Startup · Cleveland · octetsci.com
• Octin Health
  Startup · Minneapolis · octinhealth.com
• Ohm Health
  Startup · Richmond · ohm.health
• Olive
  Startup · Columbus · oliveai.com
• Onconaut Therapeutics
  Startup · Aurora · onconaut.com
• OncoVerity
  Startup · Aurora · oncoverity.com
• OpenLoop Health
  Startup · Des Moines · openloophealth.com
• Orca Advisor
  Startup · Bellefontaine · orcaadvisor.com
• Origin Therapy
  Startup · Fairfax · origintherapy.com
• orthobrain
  Startup · orthobrain.com
• Pack Moose
  Startup · Cedar Falls · emigrait.com
• Palarum
  Startup · Lebanon · palarum.com
• Palvella Therapeutics
  Startup · Wayne · palvellatx.com
• Palzaar
  Startup · Peoria · palzaar.com
• Pancopia
  Startup · Hampton · pancopia.com
• Pangea Chat
  Startup · Richmond · pangeachat.com
• Pani Clean
  Startup · Coralville · paniclean.com
• Papertrail
  Startup · Highland Heights · papertrailtech.com
• Parcell
  Startup · Columbus · parcellplus.com
• PARCO
  Startup · Richmond · goparco.com
• ParkiFi
  Startup · Denver · parkifi.com
• Parley Neurotech
  Startup · Denver · parleyneuro.com
• Parsyl
  Startup · Denver · parsyl.com
• Pathware
  Startup · Golden · pathware.com
• Payman AI
  Startup · Durango · paymanai.com
• PeachPay
  Startup · Ames · peachpay.app
• Peak Energy
  Startup · Denver · peakenergy.com
• Pearl
  Startup · Richmond · tutorwithpearl.com
• Pebble Spaces
  Startup · East Canton · pebblespaces.com
• Perspective Therapeutics
  Startup · Coralville · perspectivetherapeutics.com
• Photon Queue
  Startup · Chicago · photonqueue.com
• Physna
  Startup · physna.com
• PigEasy
  Startup · Templeton · pigeasy.com
• Pitchly
  Startup · Des Moines · pitchly.com
• Pixelar Solutions
  Startup · Newport News · pixelar.us
• planeKrafty
  Startup · Cincinnati · planekrafty.com
• Planetary Talent
  Startup · Wichita · grooverlabs.org
• Plastinuva
  Startup · Toledo · plastinuva.com
• PleoPharma
  Startup · Boca Raton · pleopharma.com
• PLOT
  Startup · Wichita · getplot.com
• PlugOp
  Startup · Columbus · plugop.com
• Pluto
  Startup · Denver · pluto.bio
• Pod Farms
  Startup · Pulaski · podfarms.com
• Point Designs
  Startup · Broomfield · pointdesigns.com
• Polaris Electro-Optics
  Startup · Boulder · polariseo.com
• Poly API
  Startup · Erie · polyapi.io
• Polymark Systems
  Startup · Cleveland · polymarksystems.com
• Portalform
  Startup · portalform.com
• Poultry Patrol
  Startup · Coralville · poultrypatrol.com
• PowerPollen
  Startup · Ames · powerpollen.com

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Cities

• Startups in Cincinnati, Ohio 69
• Startups in Boulder, Colorado 57
• Startups in Richmond, Virginia 52
• Startups in Denver, Colorado 50
• Startups in Columbus, Ohio 47
• Startups in Cleveland, Ohio 42
• Startups in Ames, Iowa 40
• Startups in Tulsa, Oklahoma 33
• Startups in Chicago, Illinois 32
• Startups in Des Moines, Iowa 31
• Startups in Oklahoma City, Oklahoma 29
• Startups in Iowa City, Iowa 28
• Startups in Norman, Oklahoma 24
• Startups in Boca Raton, Florida 22
• Startups in Charlottesville, Virginia 22
• Startups in Lawrence, Kansas 19
• Startups in Overland Park, Kansas 18
• Startups in Cedar Rapids, Iowa 16
• Startups in Coralville, Iowa 16
• Startups in Dayton, Ohio 16
• Startups in Fort Collins, Colorado 16
• Startups in Wichita, Kansas 15
• Startups in Blacksburg, Virginia 14
• Startups in Alexandria, Virginia 13
• Startups in Norfolk, Virginia 12
• Startups in Roanoke, Virginia 12
• Startups in Toledo, Ohio 12
• Startups in West Palm Beach, Florida 11
• Startups in Arlington, Virginia 10
• Startups in Aurora, Colorado 10
• Startups in Colorado Springs, Colorado 10
• Startups in Golden, Colorado 9
• Startups in Hampton, Virginia 9
• Startups in Greeley, Colorado 8
• Startups in McLean, Virginia 8
• Startups in Akron, Ohio 7
• Startups in Champaign, Illinois 7
• Startups in Dublin, Ohio 7
• Startups in Erie, Colorado 7
• Startups in Longmont, Colorado 7
• Startups in Reston, Virginia 7
• Startups in West Des Moines, Iowa 7
• Startups in Cedar Falls, Iowa 6
• Startups in Fairfield, Iowa 6
• Startups in Jupiter, Florida 6
• Startups in Leawood, Kansas 6
• Startups in Lenexa, Kansas 6
• Startups in Broomfield, Colorado 5
• Startups in Chagrin Falls, Ohio 5
• Startups in Davenport, Iowa 5
• Startups in Delray Beach, Florida 5
• Startups in Hilliard, Ohio 5
• Startups in Lafayette, Colorado 5
• Startups in Olathe, Kansas 5
• Startups in Palm Beach Gardens, Florida 5
• Startups in Ankeny, Iowa 4
• Startups in Clive, Iowa 4
• Startups in Durango, Colorado 4
• Startups in Edmond, Oklahoma 4
• Startups in Englewood, Colorado 4
• Startups in Henrico, Virginia 4
• Startups in Kansas City, Kansas 4
• Startups in Littleton, Colorado 4
• Startups in Manhattan, Kansas 4
• Startups in Mason, Ohio 4
• Startups in Sioux City, Iowa 4
• Startups in Virginia Beach, Virginia 4
• Startups in Youngstown, Ohio 4
• Startups in Buena Vista, Colorado 3
• Startups in Centennial, Colorado 3
• Startups in Council Bluffs, Iowa 3
• Startups in Fairfax, Virginia 3
• Startups in Grand Junction, Colorado 3
• Startups in Greenwood Village, Colorado 3
• Startups in Herndon, Virginia 3
• Startups in Loveland, Colorado 3
• Startups in Milford, Ohio 3
• Startups in Newport News, Virginia 3
• Startups in Prairie Village, Kansas 3
• Startups in Topeka, Kansas 3
• Startups in Urbandale, Iowa 3
• Startups in Windsor, Colorado 3
• Startups in Xenia, Ohio 3