Startups in the United States

The Innovative EcoSystems registry lists 1,456 startups in the United States.

Startups are young companies building new products or business models.

The largest concentrations are in Cincinnati, Ohio (69), Boulder, Colorado (57) and Richmond, Virginia (52).

The United States scores 68.5 out of 100 on the IEPA (2024 edition), ranking 21 of 117 economies.

See the United States on the IEPA ↗

1,456 startups

• Spotlight Innovation
  Startup · West Des Moines
• Sprayer Mods
  Startup · Iowa City
• Sprints
  Startup · Cincinnati
• Stable Laser Systems
  Startup · Boulder
• staC12
  Startup · Chicago
• Stagerie
  Startup · Clive
• Standard Space Antennas
  Startup · Boca Raton
• Standard Thermal
  Startup · Edmond
• STAT Therapeutics
  Startup · Overland Park
• STBL Strategies
  Startup · Wichita
• SteriO3
  Startup · Littleton
• SteroCore Therapeutics
  Startup · Lawrence
• StewTech
  Startup · Hampton
• Stingray Technology Solutions
  Startup · Delray Beach
• Stone Heritage Jewelry
  Startup · Mason City
• Stratica Biosciences
  Startup
• Streak Labs
  Startup · Richmond
• StrideHx
  Startup
• Stridelane
  Startup · Iowa City
• Sublime Stericeuticals
  Startup · Ames
• Sulverra
  Startup · Lawrence
• Sunzu
  Startup · Boulder
• Super.tech
  Startup · Closed · Chicago
• SuppTrax
  Startup
• SureHost
  Startup · Des Moines
• Surgical RX
  Startup · Cincinnati
• Surgiplate
  Startup · Toledo
• SusMer
  Startup · Fort Collins
• SustainaBase
  Startup · Closed · West Palm Beach
• Sustainable Chemicals
  Startup · Golden
• Swift Sync
  Startup · Miami
• Swinetech
  Startup · Solon
• SynAIpse
  Startup · Cincinnati
• Syndicate of Sound & Synapse
  Startup · Council Bluffs
• Table to Farm Compost
  Startup · Durango
• Tactical Triage Technologies
  Startup · Columbus
• TAGN
  Startup
• Tally Receipts
  Startup · Tulsa
• Tango Biosciences
  Startup · Chicago
• Team Wildfire
  Startup · Boulder
• Techam Solutions
  Startup · Wichita
• TECHnista
  Startup · Pittsylvania County
• TelePharm
  Startup · Iowa City
• Tereform
  Startup · Englewood
• TerraDAC Technologies
  Startup · Tulsa
• Terraform Tillage
  Startup · Eldora
• Terraoak
  Startup
• The Agenda. Period
  Startup · Brighton
• The American Baby Company
  Startup · West Palm Beach
• The Authentic Consortium
  Startup · Alexandria
• The B.O.B.O. Collective
  Startup
• The Market at Shop Near the Corner
  Startup · Le Mars
• The Mindful Mamas Club
  Startup · Closed · Englewood
• The Music Advocacy Project
  Startup
• Theion Agriculture
  Startup · Iowa City
• Thema Brain Health
  Startup · Boca Raton
• TidalMed
  Startup
• TIFIN AXIS
  Startup · Boulder
• Tiga AI
  Startup · Herndon
• Tipico Helado
  Startup · Council Bluffs
• TissueVue
  Startup · Cincinnati
• Titan Intake
  Startup · Tulsa
• Toadworx
  Startup · Wichita
• Tobe Energy
  Startup · Oklahoma City
• Tolefin
  Startup
• Tracer
  Startup · Golden
• TrAMPoline Pharma
  Startup · Aurora
• Travv
  Startup · Stillwater
• Trellisense
  Startup · Superior
• Triangulate Labs
  Startup
• Trovio
  Startup · Cincinnati
• True360
  Startup · Ames
• Trusted Therapy Network
  Startup
• TuitionFit
  Startup · Davenport
• Tumbleweed
  Startup
• Unlisted Homes
  Startup · Dayton
• Unspent
  Startup · Columbus
• Upcycling+
  Startup · Ames
• UpStream
  Startup · North Liberty
• Urban Farms
  Startup · Boulder
• Urban Reblok’d
  Startup · Roanoke
• US Mission Labs
  Startup
• UV Concepts
  Startup · Englewood
• Vectoryx
  Startup
• Velocity AI Partners
  Startup
• Velora
  Startup
• Vertex
  Startup · Ames
• Vesica Pulse Sensing
  Startup · Boca Raton
• Vesicle Therapeutics
  Startup · Boulder
• Vespr Solar
  Startup · Norman
• Vet Measure
  Startup · Ames
• Vexlum
  Startup · Broomfield
• VHSMO
  Startup · Cincinnati
• VIAS Campus Management (Praxis Campus Management Software, Inc.)
  Startup · Oklahoma City
• Vicory Solutions
  Startup · Iowa City
• Vidnova Therapeutics
  Startup
• Vina
  Startup · Stockton
• VisioCell
  Startup · Toledo
• VisiPay
  Startup · Olathe
• Vital Foams
  Startup · Fort Collins
• Viva Fit Kitchen
  Startup · Council Bluffs
• VOISS
  Startup · Lawrence
• Vortex Biotechnology
  Startup · Westminster
• Vosmosis
  Startup
• Vytas Bio
  Startup · Lawrence
• Waderbuddy
  Startup
• Warp Zone
  Startup · Sioux City
• Waste2Wealth
  Startup · Blacksburg
• WaterWise Technologies
  Startup · Columbus
• Watkins-Conti Products
  Startup · Edmond
• WearLab Solutions
  Startup
• Weather Decision Technologies (WDT)
  Startup · Norman
• WeatherDeep
  Startup · Norman
• Weaver Labs
  Startup · Stillwater
• WebCareHealth
  Startup · Ankeny
• WELD
  Startup · Oklahoma City
• Westwin Elements
  Startup · Oklahoma City
• WINPRO Pet
  Startup · Des Moines
• Work N Walter Farms
  Startup · Cedar Falls
• Workgroups DaVinci
  Startup · Des Moines

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Cities

• Startups in Cincinnati, Ohio 69
• Startups in Boulder, Colorado 57
• Startups in Richmond, Virginia 52
• Startups in Denver, Colorado 50
• Startups in Columbus, Ohio 47
• Startups in Cleveland, Ohio 42
• Startups in Ames, Iowa 40
• Startups in Tulsa, Oklahoma 33
• Startups in Chicago, Illinois 32
• Startups in Des Moines, Iowa 31
• Startups in Oklahoma City, Oklahoma 29
• Startups in Iowa City, Iowa 28
• Startups in Norman, Oklahoma 24
• Startups in Boca Raton, Florida 22
• Startups in Charlottesville, Virginia 22
• Startups in Lawrence, Kansas 19
• Startups in Overland Park, Kansas 18
• Startups in Cedar Rapids, Iowa 16
• Startups in Coralville, Iowa 16
• Startups in Dayton, Ohio 16
• Startups in Fort Collins, Colorado 16
• Startups in Wichita, Kansas 15
• Startups in Blacksburg, Virginia 14
• Startups in Alexandria, Virginia 13
• Startups in Norfolk, Virginia 12
• Startups in Roanoke, Virginia 12
• Startups in Toledo, Ohio 12
• Startups in West Palm Beach, Florida 11
• Startups in Arlington, Virginia 10
• Startups in Aurora, Colorado 10
• Startups in Colorado Springs, Colorado 10
• Startups in Golden, Colorado 9
• Startups in Hampton, Virginia 9
• Startups in Greeley, Colorado 8
• Startups in McLean, Virginia 8
• Startups in Akron, Ohio 7
• Startups in Champaign, Illinois 7
• Startups in Dublin, Ohio 7
• Startups in Erie, Colorado 7
• Startups in Longmont, Colorado 7
• Startups in Reston, Virginia 7
• Startups in West Des Moines, Iowa 7
• Startups in Cedar Falls, Iowa 6
• Startups in Fairfield, Iowa 6
• Startups in Jupiter, Florida 6
• Startups in Leawood, Kansas 6
• Startups in Lenexa, Kansas 6
• Startups in Broomfield, Colorado 5
• Startups in Chagrin Falls, Ohio 5
• Startups in Davenport, Iowa 5
• Startups in Delray Beach, Florida 5
• Startups in Hilliard, Ohio 5
• Startups in Lafayette, Colorado 5
• Startups in Olathe, Kansas 5
• Startups in Palm Beach Gardens, Florida 5
• Startups in Ankeny, Iowa 4
• Startups in Clive, Iowa 4
• Startups in Durango, Colorado 4
• Startups in Edmond, Oklahoma 4
• Startups in Englewood, Colorado 4
• Startups in Henrico, Virginia 4
• Startups in Kansas City, Kansas 4
• Startups in Littleton, Colorado 4
• Startups in Manhattan, Kansas 4
• Startups in Mason, Ohio 4
• Startups in Sioux City, Iowa 4
• Startups in Virginia Beach, Virginia 4
• Startups in Youngstown, Ohio 4
• Startups in Buena Vista, Colorado 3
• Startups in Centennial, Colorado 3
• Startups in Council Bluffs, Iowa 3
• Startups in Fairfax, Virginia 3
• Startups in Grand Junction, Colorado 3
• Startups in Greenwood Village, Colorado 3
• Startups in Herndon, Virginia 3
• Startups in Loveland, Colorado 3
• Startups in Milford, Ohio 3
• Startups in Newport News, Virginia 3
• Startups in Prairie Village, Kansas 3
• Startups in Topeka, Kansas 3
• Startups in Urbandale, Iowa 3
• Startups in Windsor, Colorado 3
• Startups in Xenia, Ohio 3