Startups in the United States

The Innovative EcoSystems registry lists 1,456 startups in the United States.

Startups are young companies building new products or business models.

The largest concentrations are in Cincinnati, Ohio (69), Boulder, Colorado (57) and Richmond, Virginia (52).

The United States scores 68.5 out of 100 on the IEPA (2024 edition), ranking 21 of 117 economies.

See the United States on the IEPA ↗

1,456 startups

• MicroFinance Pro
  Startup · West Palm Beach
• MiDi
  Startup · Des Moines
• MindMode AI
  Startup
• Mined XAI
  Startup · Dayton
• Moat Biotechnology (MoatBio)
  Startup · Oklahoma City
• MobilePantry
  Startup · Columbus
• Modendo
  Startup · Boulder
• Modern Reproduction
  Startup · Roanoke
• Molecular Interfaces
  Startup · Chicago
• Moleculera Biosciences
  Startup · Oklahoma City
• Momentum Optics
  Startup · Longmont
• Monarch Health Systems
  Startup
• Monte Caldera Technologies
  Startup · Tulsa
• Moonnox
  Startup · Closed · Chicago
• Motiv
  Startup
• Motive
  Startup · Oklahoma City
• MSUITE
  Startup · Cedar Rapids
• Muse
  Startup · Oklahoma City
• Music League
  Startup · Des Moines
• My Autonomous Transportation Co.
  Startup
• My Health Sentry
  Startup · Shawnee
• MyAniml
  Startup · Overland Park
• MyFutureSelf
  Startup · Cincinnati
• Myndset
  Startup · Lawrence
• Myonexus Therapeutics
  Startup · Closed · Columbus
• Myri Health
  Startup · Oklahoma City
• N-Sense
  Startup · Ames
• Nabu Optical Systems
  Startup · Dayton
• Nano Gas
  Startup · Deerfield
• NanoSpy
  Startup · Ames
• NarrateAR
  Startup · Ames
• Narratize
  Startup · Cincinnati
• Natrion
  Startup · Champaign
• Natural Solutions
  Startup · Pittsburg
• NavaFlex
  Startup · Worthington
• Navigator (GovFunds, Inc.)
  Startup · Tulsa
• NearStar Fusion
  Startup · Chantilly
• NebulaNeuro
  Startup · Roanoke
• NecoTech
  Startup · Delaware
• Nectagen
  Startup · Lawrence
• NeoVaxSyn
  Startup · Ames
• NEPTUNYA Ocean Power
  Startup · Boca Raton
• Nestera
  Startup
• NETenergy
  Startup · Chicago
• NetNeural
  Startup · Cincinnati
• NeuroLife
  Startup · Columbus
• New West Genetics
  Startup · Fort Collins
• Nichefire
  Startup · Columbus
• Noah System
  Startup · Chicago
• NoctIQ
  Startup · Richmond
• Nodecraft
  Startup · Oklahoma City
• Noonan
  Startup · Lenexa
• NOVI SPACE
  Startup · Arlington
• Noviqu
  Startup · Cedar Rapids
• Novprox
  Startup · Boca Raton
• Nuvint AI
  Startup
• Oak Therapeutics
  Startup · Lawrence
• Occlusion Solutions
  Startup · Tulsa
• Octave Photonics
  Startup · Louisville
• OMC Hydrogen
  Startup · Fort Collins
• Onca Bio
  Startup
• OnlineVisas
  Startup · Norman
• OnSight
  Startup · Spring Hill
• Open NeuroTech
  Startup
• Opera Bioscience
  Startup · Evanston
• Opine AI
  Startup
• OptoKhemia Analytical
  Startup · Norman
• ORAN Development Co.
  Startup · Arlington
• Oravadra
  Startup
• Ordermatic
  Startup
• OrganiCore Nuclear
  Startup · Reston
• Origami Space Development
  Startup · Berthoud
• Origin Healthcare
  Startup · Fort Collins
• Orion Labs
  Startup · Nunn
• OrisDX
  Startup
• Osmopure Technologies
  Startup · Boulder
• Ossatura Labs
  Startup · Toledo
• Oto-Biomechanics LLC
  Startup · Norman
• Otoro Energy
  Startup · Boulder
• Overwatch Technologies
  Startup · Wichita
• P3 Technologies
  Startup · Martin County
• PACT Outdoors
  Startup · Crested Butte
• Palanquin Power
  Startup · Golden
• Pantomath
  Startup · Cincinnati
• Panty Promise
  Startup · West Palm Beach
• ParaNano Wound Care
  Startup · Oklahoma City
• Parasol
  Startup · Closed · Richmond
• Parasol Medtech
  Startup · Chicago
• Parman Tech
  Startup · Loveland
• Pascal Medical
  Startup · Richmond
• Pattern Labs
  Startup · Erie
• Pavaka Wound Care
  Startup · Columbus
• Payfactory
  Startup · Tulsa
• Payload
  Startup · Cincinnati
• Peaks Precast
  Startup · Buena Vista
• Pear Deck
  Startup · Iowa City
• Penti
  Startup · Boca Raton
• Percipio Health
  Startup · Tulsa
• Perfusion Medical
  Startup · Reston
• Perthera
  Startup · McLean
• Petrost Therapeutics
  Startup · Iowa City
• PHAXTEC
  Startup · Fort Collins
• PherDal Fertility Science
  Startup
• Phoreus Biotechnology
  Startup · Lawrence
• PhotonPharma
  Startup · Fort Collins
• PicklePlay
  Startup · Cedar Falls
• PickNik Robotics
  Startup · Boulder
• Pieces
  Startup · Cincinnati
• Pitchster
  Startup · Olathe
• Plasmole
  Startup · Cincinnati
• playhaus
  Startup · Kansas City
• PlayTime Movement
  Startup · Toledo
• Pocket Keys
  Startup · Topeka
• POGO (Property Operations On the Go)
  Startup · Oklahoma City
• Poiesis Medical
  Startup · Jupiter
• Point Solutions Security
  Startup · Denver
• PointPro
  Startup · Columbus
• Popper Pets
  Startup · Iowa City
• Portfolio Sight
  Startup
• Prairie Biosciences
  Startup · Oklahoma City

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Cities

• Startups in Cincinnati, Ohio 69
• Startups in Boulder, Colorado 57
• Startups in Richmond, Virginia 52
• Startups in Denver, Colorado 50
• Startups in Columbus, Ohio 47
• Startups in Cleveland, Ohio 42
• Startups in Ames, Iowa 40
• Startups in Tulsa, Oklahoma 33
• Startups in Chicago, Illinois 32
• Startups in Des Moines, Iowa 31
• Startups in Oklahoma City, Oklahoma 29
• Startups in Iowa City, Iowa 28
• Startups in Norman, Oklahoma 24
• Startups in Boca Raton, Florida 22
• Startups in Charlottesville, Virginia 22
• Startups in Lawrence, Kansas 19
• Startups in Overland Park, Kansas 18
• Startups in Cedar Rapids, Iowa 16
• Startups in Coralville, Iowa 16
• Startups in Dayton, Ohio 16
• Startups in Fort Collins, Colorado 16
• Startups in Wichita, Kansas 15
• Startups in Blacksburg, Virginia 14
• Startups in Alexandria, Virginia 13
• Startups in Norfolk, Virginia 12
• Startups in Roanoke, Virginia 12
• Startups in Toledo, Ohio 12
• Startups in West Palm Beach, Florida 11
• Startups in Arlington, Virginia 10
• Startups in Aurora, Colorado 10
• Startups in Colorado Springs, Colorado 10
• Startups in Golden, Colorado 9
• Startups in Hampton, Virginia 9
• Startups in Greeley, Colorado 8
• Startups in McLean, Virginia 8
• Startups in Akron, Ohio 7
• Startups in Champaign, Illinois 7
• Startups in Dublin, Ohio 7
• Startups in Erie, Colorado 7
• Startups in Longmont, Colorado 7
• Startups in Reston, Virginia 7
• Startups in West Des Moines, Iowa 7
• Startups in Cedar Falls, Iowa 6
• Startups in Fairfield, Iowa 6
• Startups in Jupiter, Florida 6
• Startups in Leawood, Kansas 6
• Startups in Lenexa, Kansas 6
• Startups in Broomfield, Colorado 5
• Startups in Chagrin Falls, Ohio 5
• Startups in Davenport, Iowa 5
• Startups in Delray Beach, Florida 5
• Startups in Hilliard, Ohio 5
• Startups in Lafayette, Colorado 5
• Startups in Olathe, Kansas 5
• Startups in Palm Beach Gardens, Florida 5
• Startups in Ankeny, Iowa 4
• Startups in Clive, Iowa 4
• Startups in Durango, Colorado 4
• Startups in Edmond, Oklahoma 4
• Startups in Englewood, Colorado 4
• Startups in Henrico, Virginia 4
• Startups in Kansas City, Kansas 4
• Startups in Littleton, Colorado 4
• Startups in Manhattan, Kansas 4
• Startups in Mason, Ohio 4
• Startups in Sioux City, Iowa 4
• Startups in Virginia Beach, Virginia 4
• Startups in Youngstown, Ohio 4
• Startups in Buena Vista, Colorado 3
• Startups in Centennial, Colorado 3
• Startups in Council Bluffs, Iowa 3
• Startups in Fairfax, Virginia 3
• Startups in Grand Junction, Colorado 3
• Startups in Greenwood Village, Colorado 3
• Startups in Herndon, Virginia 3
• Startups in Loveland, Colorado 3
• Startups in Milford, Ohio 3
• Startups in Newport News, Virginia 3
• Startups in Prairie Village, Kansas 3
• Startups in Topeka, Kansas 3
• Startups in Urbandale, Iowa 3
• Startups in Windsor, Colorado 3
• Startups in Xenia, Ohio 3